All pregnant women in the U.S. should be assessed for possible Zika exposure during every prenatal visit, the Centers for Disease Control and Prevention said Monday.

The advice from the CDC came as federal health officials also urged women who are pregnant or are considering becoming pregnant to avoid a Miami neighborhood that is the site of a Zika outbreak.

Zika can cause catastrophic birth defects in developing fetuses, including microcephaly, which results in an abnormally small skull and, in most cases, incomplete brain development. The CDC has warned pregnant women since January to avoid areas with Zika outbreaks. Until now, those travel warnings were limited to foreign countries and U.S. territories, such as Puerto Rico and the U.S. Virgin Islands.

Now, the CDC warns pregnant women to avoid the Wynwood neighborhood in Miami, where 14 people have been infected with Zika. That move appears to be unprecedented in CDC history.

While pregnant women don't automatically needed to be tested for Zika, healthcare providers should ask women about recent travel, as well as any travel by her sexual partner.

Those who should be tested include pregnant women with symptoms of Zika, which include a fever and rash, as well as pregnant women who may have been exposed through travel or sex, according to the CDC.

Pregnant women who live in or frequently travel to Wynwood to be tested for Zika in the first and second trimester, the CDC said. The CDC advises all pregnant women to avoid mosquito bites, through wearing long sleeves and insect repellent, especially if they live in an area with the main mosquito species that spreads Zika, the Aedes aegypti. These mosquitoes live in 30 states and several territories, including Puerto Rico.

The CDC also advised the sex partners of pregnant women to protect these women from Zika infection. Sexual partners of pregnant women who have traveled to Wynwood, or other areas with Zika outbreaks, should use condoms or other barrier methods for the rest of a woman's pregnancy, the CDC said.

Couples planning to become pregnant should also consider their risk of Zika, the CDC said. Women and men who have traveled to Wynwood since June 15 should wait at least eight weeks before trying to conceive a child, according to the CDC. Women and men who live in Wynwood or frequently travel there should talk to their healthcare provider.